Topological Indices Study of Molecular Structure Hyaluronic Acid-Paclitaxel Conjugates in Cancer Treatment

Zhuang J., Shooshtari H., Cancan M.

Polycyclic Aromatic Compounds, cilt.44, sa.3, ss.1793-1804, 2024 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 3
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1080/10406638.2023.2207776
  • Dergi Adı: Polycyclic Aromatic Compounds
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Applied Science & Technology Source, CAB Abstracts, Chemical Abstracts Core, Communication Abstracts, Food Science & Technology Abstracts, Metadex, Pollution Abstracts, Veterinary Science Database, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.1793-1804
  • Anahtar Kelimeler: Cancer treatment, chemical graph, hyaluronic acid-paclitaxel conjugates
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

A large number of medical experiments have confirmed that the features of drugs have a close correlation with their molecular structure. Drug properties can be obtained by studying the molecular structure of corresponding drugs. The calculation of the topological index of a drug structure enables scientists to have a better understanding of the physical chemistry and biological characteristics of drugs. In this paper, we obtain the exact formulas by virtue of the edge-partition method for (Formula presented.) and (Formula presented.) By the appropriate choice of parameters (Formula presented.) and (Formula presented.) several new/old inequalities that reveal relationships between various topological indices are obtained. Our results remedy the lack of medicine experiments, thus providing a theoretical basis for pharmaceutical engineering.