Akademik Veri Yönetim Sistemi
Tezin Türü: Doktora
Tezin Yürütüldüğü Kurum: Van Yüzüncü Yıl Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Türkiye
Tezin Onay Tarihi: 2023
Tezin Dili: Türkçe
Öğrenci: Enes Abdurrahman Bilgin
Danışman: Sıddık Keskin
Özet:
In this study, it is aimed to design an
application that will facilitate statistical analyzes for the concept of
biological variation, which is frequently used in order to test the reliability
of measurements in the fields of Medicine and Biochemistry and to obtain new
reference intervals. In this research, carried out according to the Design and
Development research method, in which a product is revealed at the end of the
process, theoretical information about the Nested Anova analysis, which
constitutes the mathematical infrastructure of biological variation, was given,
and then algorithms were developed in Excel VBA in accordance with the
mathematical model. Then, macros were created to obtain biological variation
parameters according to Fraser's model from the analysis of variance findings.
With the help of the obtained application, calculations were made for some data
sets whose results are already known, and the results were compared. As a
result, it has been seen that the application developed as a result of the
research performs the Nested Anova analysis without error, and also correctly
calculates the variance components obtained from the Anova table. It is
expected that the obtained application will provide convenience to researchers
doing research on the subject.