Effectiveness of Twin-Beam Dual-Energy Computed Tomography in Characterization of Solitary Pulmonary Nodules

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Tezin Türü: Tıpta Uzmanlık

Tezin Yürütüldüğü Kurum: Van Yüzüncü Yıl Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Türkiye

Tezin Onay Tarihi: 2020

Tezin Dili: Türkçe

Öğrenci: SAİM TÜRKOĞLU

Danışman: Saim Türkoğlu, Mesut Özgökçe

Özet:

Abstract

 

Objective: The aim of this study is to investigate the effectiveness of Dual-Energy Computed Tomography including visual assessment, iodine concentration, and contrast load for the discrimination between benign and malignant pulmonary nodules.

 

Materials and Methods: The images of the patients with 53 pulmonary nodules that were taken with dual energy thoracic computed tomography, 40 seconds after intravenous contrast administration, were obtained with a single-source dual-energy computed tomography (120kV Split Filter) with twin beam technology, and a dual-energy was done at work station (SyngoVia; Siemens Medical Solutions). Color map evaluation findings in visual enhancement, contrast and iodine loads were calculated and noted separately for each of the 53 solitary lung nodules.

 

Results: A total of 53 patients 26 (49%) male and 27 (51%) female) with a solitary pulmonary nodule fulfilled the inclusion criteria. Among 53 pulmonary nodules, 17 (32.1%) were malignant and 36 (67.9%) were benign. Of the benign lesions; 18 were detected in males (30.7%) and 18 in females (33.3%).

There was not a statistically significant difference in age between two groups (p=0.284).

The mean contrast load of the malignant nodules is significantly higher than that of benign nodules  (p=0.034). The mean iodine load of the malignant nodules is significantly higher than that of benign nodules (p=0.031).  The frequency of red/orange appearance was significantly higher in malignant nodules than benign ones (p:0.006).

 

Conclusion: We think that dual-energy computed tomography will make significant contributions to the differentiation of benign and malignant in solitary pulmonary nodular lesions detected in the lung, with three different approaches such as visual on the image on the iodine coating color map, iodine concentration and iodine contrast load quantitatively.

 

Keywords: Dual Energy, Benign, Malignant, Pulmonary Nodule, Twin-beam, Iodine map, Contrast load, Iodine load