Regulation of Glutathione S-Transferase Mu with type 1 diabetes and its regulation with antioxidants

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Sadi G., Kartal D., GÜRAY N. T.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.38, sa.1, ss.92-100, 2013 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.5505/tjb.2013.96720
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.92-100
  • Anahtar Kelimeler: GST-Mu, gene expression, lipid peroxidation, protein carbonylation, diabetes mellitus, ALPHA-LIPOIC ACID, OXIDATIVE STRESS, LIPID-PEROXIDATION, ENZYME-ACTIVITIES, GENE-EXPRESSION, VITAMIN-C, RATS, PROTECTION, LOCALIZATION, MODULATION
  • Van Yüzüncü Yıl Üniversitesi Adresli: Hayır

Özet

Objective: Increased oxidative stress is now related with the pathogenesis and the chronic complications associated with the disease, diabetes mellitus. While roles of oxidative stress in diabetic complications are widely studied, the molecular mechanisms playing role in the regulations of detoxification enzymes in the presence of antioxidants have not been clearly established because of the complexity of the pathways.