Objective: The aim of the present study was to discuss and compare the clinical outcomes and thyroid functions of complete and incomplete mole pregnancies in the highlights of the literature. Materials and Methods: The study was conducted at a University Hospital, Department of Obstetrics and Gynecology between January 2006 and January 2016. The clinical outcomes and thyroid function tests of 242 complete and incomplete mole pregnancies were reviewed retrospectively. The patients were divided into two groups as, 127 pregnancies with complete mole and 115 pregnancies with incomplete mole. Results: The mean maternal age of complete and incomplete mole pregnancies were 33.87±12.14 and 31.73±10.12, respectively. There was no significant difference between the groups (p: 0.139). The mean TSH values of complete and incomplete mole pregnancies were 0.5±0.9 mIU/ml and 1.0±1.2 mIU/ml, respectively. The mean TSH values were higher in incomplete mole pregnancies than in complete mole pregnancies (p:0.001). Conclusion: The present study showed that thyroid functions were not affected clinically in mole pregnancies for the follow-up and management of the patients. However, we still recommended that the thyroid functions should be evaluated in mole pregnancies, to prevent the mortal complications of hyperthyroidism.