Akademik Veri Yönetim Sistemi
Tezin Türü: Yüksek Lisans
Tezin Yürütüldüğü Kurum: Van Yüzüncü Yıl Üniversitesi, Fen Bilimleri Enstitüsü, Kimya (Yl) (Tezli), Türkiye
Tezin Onay Tarihi: 2025
Tezin Dili: İngilizce
Öğrenci: BAFREEN JAAFAR MOHAMMED SALEEM HAMOSI
Danışman: Tülay Gürsoy
Özet:
Molecularly imprinted polymers (MIPs) are
defined as functional molecules that can recognize and respond to specific,
biological and chemical agents. In this study, a novel MIP-based solid-phase
extraction (SPE) material was developed by surface imprinting on bentonite
(BNT) for the selective separation and determination of profenofos (PFF), a
widely used organophosphorus pesticide. The MIP-BNT composite was synthesized
via surface-initiated free radical polymerization and the successful
modification was confirmed by combination of surface characterization
techniques. The results showed that the MIP-BNT exhibited high surface area,
uniform morphology, and specific binding sites tailored for PFF recognition.
Adsorption kinetics followed a pseudo-second-order model, and isotherm analysis
fitted well to the Langmuir model, suggesting monolayer adsorption. The method
was optimized in terms of SPE parameters such as pH, sorbent amount, desorption
time, and eluent volume to ensure maximum recovery and reproducibility. The
developed MIP-SPE integrated with UV–vis spectrophotometry demonstrated
excellent linearity (0.1–270 µM), low detection limit (0.0334 µM), high
enrichment factor (EF = 74), and good reusability (at least 8 cycles) without
significant performance loss. Recovery studies in food and water samples
(tomato, cabbage, spring onion, apple, orange, lake water, and drinking water)
yielded values ranging from 94.0% to 100.4% with RSDs below 5%, and results
were in agreement with those obtained by HPLC. Compared to existing methods,
the developed approach offers a cost-effective, eco-friendly, and selective
alternative for routine monitoring of PFF residues in various food and water
samples.
The development of molecularly imprinted
nano- and microstructures, magnetic and fluorescent composite materials,
ratiometric chemical sensors, and catalytic MIPs fulfills scientific functions
with broad scope.
Keywords:
Bentonite clay, Molecularly imprinted polymer,
Profenofos, Solid-phase extraction, UV-vis spectrophotometry