The aim of the study was to determine the total phenolic (TPC) and flavonoid (TF) contents of some medicinal plants grown in Caldiran/Van that are frequently consumed by people and to reveal possible differences in the water extracts obtained from different organs. Alcea pallida (Willd.) Waldst. &. Kit. Rumex scutatus L., Mentha longifolia (L.) L., Erigeron acris L., Achillea vermicularis Trin. were collected from Caldiran/Van. TPC and TF contents of the extracts were measured spectrophotometrically. The highest TPC and TF were obtained from the seed extract of E. acris. Stem extracts of the same plant and the stem and seed extracts of M. longifolia were also the samples carrying high phenolic and flavonoids. As a result, it was shown that the flower and seed extracts of five different plants were more efficient than the stem extracts. Biochemical profiles of E. acris and M. longifolia showed that these plants can be used for medicinal purposes and both seed and stem parts contain notably high levels of phenolic and flavonoids.