An investigation of the relation between catalase C262T gene polymorphism and catalase enzyme activity in leukemia patients

ERAS N., Turkoz G., TOMBAK A., Tiftik N., YALIN S., Berköz M., ...Daha Fazla

ARCHIVES OF MEDICAL SCIENCE, cilt.17, sa.4, ss.928-933, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 4
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5114/aoms.2019.89692
  • Dergi Adı: ARCHIVES OF MEDICAL SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, Veterinary Science Database, Directory of Open Access Journals
  • Sayfa Sayıları: ss.928-933
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Introduction: Catalase (CAT), an antioxidant enzyme, catalyzes conversion of hydrogen peroxide to water and molecular oxygen, protecting cells against oxidative stress. The aim of this study was to investigate the possible association between CAT C262T polymorphism in the promoter region of the CAT gene and leukemia risk and to determine the relationship between CAT genotypes and CAT enzyme activities.