Pleuropericarditis Associated with Sulphasalazine in a Case of Rheumatoid Arthritis: A Drug-Induced Lupus-Like Syndrome

Hiz O., Gulcu E., Ozkan Y., Tekeoglu I., Aladag N.

TURKISH JOURNAL OF RHEUMATOLOGY, cilt.26, sa.3, ss.248-253, 2011 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 3
  • Basım Tarihi: 2011
  • Doi Numarası: 10.5152/tjr.2011.039
  • Dergi Adı: TURKISH JOURNAL OF RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.248-253
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Pericarditis, a life-threatening condition, can be seen in rheumatic diseases. It may occur secondary to rheumatic diseases or drugs used in the treatment. In this article, we present a case of 47-year-old female, who had joint complaints for 15 years and had treatment of methotrexate and corticosteroid for six years. In the last three months, after the addition of sulphasalazine to her treatment, she developed chest pain, palpitations, rash, fever, and pleuropericarditis and was subsequently diagnosed with systemic lupus erythematosus induced by sulfasalazine. When cardiac disease is seen in a patient with rheumatoid arthritis, medication should be discontinued immediately, and it should be kept in mind that cardiac involvement may be associated with drugs.