An interesting synthesis method for 2-acetate-1-(2-pyrrolidinone)-butane-1,3-dione compounds was developed in this work. The synthesis of these compounds was carried out in three steps. In the first step, 2-pyrrolidone derivatives were obtained by the Friedel-Crafts reaction in presence of Eaton's reagent. Then, -NH group of 2-pyrrolidone compounds were attached acetoacetate group in presence of 2,6-trimethyl-4H-1,3-dioxin-4-one reagent. Lastly, 1-(2-pyrrolidinone)-butane-1,3-dione derivatives were reacted with Pida to attach acetoxy group to these compound's methylene.