Effects of adipose and bone marrow-derived mesenchymal stem cells on vaginal atrophy in a rat menopause model


Kasap B., Kasap S., Vatansever S., Kendirci R., YILMAZ O., Calisir M. , ...More

GENE, vol.711, 2019 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 711
  • Publication Date: 2019
  • Doi Number: 10.1016/j.gene.2019.06.027
  • Title of Journal : GENE
  • Keywords: Adipogenic derived mesenchymal stem cells, Bone marrow derived mesenchymal stem cells, Menopause, Rat, Vaginal atrophy, DEHYDROEPIANDROSTERONE, EXPRESSION, SECRETOME, ESTROGEN, RECEPTOR, LIVER

Abstract

Background & objectives: Vaginal atrophy is characterized by thinning of vaginal epithelial layers and decreased local blood flow. We aimed to evaluate the regenerative effects of Adipose derived mesenchymal stem cells (ADMSC) and Bone marrow derived mesenchymal stem cells (BMDSC) on vaginal atrophy in rat menopause model.