Evaluation of Antibiotic Resistance Rates of Klebsiella pneumoniae Isolated From Patients with Bloodstream Infection

Akgül Ö.

International Journal of Scientific and Technological Research, vol.6, no.3, pp.73-79, 2020 (Peer-Reviewed Journal)


Klebsiella pneumoniae accounts for more than 70% of human infections. Especially K. pneumoniae is considered as a significant cause of bloodstream-associated infections (BSIs), urinary tract infections (UTIs), and respiratory tract infections in neonatal and intensive care units. A total of 316 K. pneumoniae, 168 isolates from male and 148 isolates from female patients, were isolated from the blood cultures of intensive care patients in Van Training and Research Hospital of the University of Health Sciences. The highest isolation was detected in the age group of “72<” in the male and female patients. The lowest isolation rates were observed in the age group of “18-36” in the male patients and “36-54” in the female patients. Extended-spectrum β-lactamase (ESBLs) and Carbapenemase (CP) productions of 316 K. pneumoniae isolates were evaluated by antibiotic resistance results. Two hundred and fifty K. pneumoniae strains isolated from the patients were observed to be ESBL positive. CP productions of 132 of the 316 K. pneumoniae isolates were revealed to be positive. It was concluded that K. pneumoniae strains, which cause circulatory system infections in our region, had high ESBLs and CP resistance, and it was important to analyze them accurately by sex, age, and antibiotic resistance.