The Correlation between Red Blood Cell Distribution Width Levels with the Severity of Obstructive Sleep Apnea and Carotid Intima Media Thickness

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Günbatar H., SERTOGULLARINDAN B., Ekin S., Akdag S., Arisoy A., SAYHAN H.

MEDICAL SCIENCE MONITOR, vol.20, pp.2199-2204, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20
  • Publication Date: 2014
  • Doi Number: 10.12659/msm.891001
  • Journal Name: MEDICAL SCIENCE MONITOR
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2199-2204
  • Keywords: Carotid Intima-Media Thickness, Erythrocyte Indices, Sleep Apnea, Obstructive, MEAN PLATELET VOLUME, CARDIOVASCULAR-DISEASE, AORTIC STIFFNESS, BRACHIAL-ARTERY, RISK, ATHEROSCLEROSIS, PREDICTORS, ACTIVATION, MECHANISMS, INFARCTION
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

Background: Obstructive sleep apnea syndrome (OSAS) is characterized by repetitive collapse of the upper airway during sleep. Red blood cell distribution width (RDW) increases platelet activation and has been reported as an independent predictor of adverse outcomes in the general population and is believed to be associated with cardiovascular morbidity and mortality. We evaluated RDW, mean platelet volume (MPV), and platelet distribution width (PDW) as a severity index in OSAS and the relationship between carotid intima media thickness and pulmonary hypertension.