Second International Congress on Biological and Health Sciences, Afyonkarahisar, Türkiye, 24 Şubat - 27 Nisan 2022, ss.314
Anaplasma species are intracellular rickettsial pathogens transmitted by ticks that have an impact on human
and animal health. Anaplasma agents infect goats in many parts of the world and methods such as Giemsa
staining, PCR and ELISA are used for diagnosis. Anemia, high fever, weight loss, abortion and jaundice can be
seen in severe anaplasma infections in goats. It was aimed to investigate the relationship between kisspeptin
levels and rare abortions, which is one of the anaplasma results. Kisspeptins are a neuropeptide produced by
hypothalamic neurons that act as upstream stimulators of gonadotropin-releasing hormone (GnRH) neurons.
The study material consisted of blood samples taken from 45 goats. Determination of control and patient
groups was made with the help of clinical signs of the disease, giemsa stained blood smears and serological
method (cELISA). The experimental group consisted of 35 goats with positive results, and 10 goats with
negative results for the control group. Kisspeptin levels were determined in the sera obtained from the
blood samples taken with the ELISA (goat Kisspeptin 1 ELISA Kit) kit. Kisspeptin level was higher in
anaplasmasis goat group compared to healthy goat group. As a result, it was determined that the kisspeptin
level was increased in the anaplasmosis group and presented to the literature.