Pantoprazole may improve beta cell function and diabetes mellitus

INCI, F.; ATMACA, M.; Öztürk, Murat; Yıldız, Saliha; KOCEROGLU, R.; Sekeroglu, Mehmet; Ipekci, S.; Kebapcilar, L.

doi:10.1007/s40618-013-0040-y

Pantoprazole may improve beta cell function and diabetes mellitus

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INCI F., ATMACA M., Öztürk M., Yıldız S., KOCEROGLU R., Sekeroglu R., ...More

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, vol.37, no.5, pp.449-454, 2014 (SCI-Expanded)

Publication Type: Article / Article
Volume: 37 Issue: 5
Publication Date: 2014
Doi Number: 10.1007/s40618-013-0040-y
Journal Name: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.449-454
Van Yüzüncü Yıl University Affiliated: Yes

Abstract

Background Proton pump inhibitors induce hypergastrinemia by suppressing gastric acidity. Gastrin has incretin-like stimulating actions on beta cells. Proton pump inhibitors have been shown to decrease glycosylated hemoglobin. Aim We aimed to observe changes in beta cell function in diabetic and non-diabetic subjects given pantoprazole for an acid-related ailment.