In this study, it is aimed to examine the level of some elements (zinc (Zn), chromium (Cr), lead (Pb), and cadmium (Cd)), and some liver enzymes (AST, ALT) in the blood-serum of workers at car-repairing shops in the vicinity of Van, Turkey. Examining material was made from the blood taken from the workers at the car-repairing shops, and from those who live far away of that cite as control. Personal habits were taken into consideration while this investigation was fulfilled. It was found that for the workers at the car-repairing shops, the quantity of AST was 27.31 +/- 9.50 U/L and for the control group it was 19.56 +/- 4.97 U/L. For the workers at the car-repairing shops and the control group the quantity of ALT was 35.00 +/- 12.62 U/L and 18.72 +/- 4.70 U/L respectively. It was significantly lower in the group with the workers at the car-repairing shops patients than in the control group (P<0.001). The level of Pb in the blood samples of the workers was 0.0630 +/- 0.051 mu g/100ml, while in the blood of the control group it was 0.0240 +/- 0.017 mu g/100ml and Pb level was significantly higher than those of controls (P<0.05). The Cd level of the blood samples was 0.0058 +/- 0.002 mu g/100ml, and in the control group it was 0.0028 +/- 0.002 mu g/100ml and serum Cd levels were found increased in the workers group than in the control (P<0.05). The quantity of Zn was found 0.3800 +/- 0.085 mu g/100ml for the workers, and for the control group it was 0.3400 +/- 0.062 mu g/100ml. The Cr quantity was found 0.077 +/- 0.011 mu g/100ml, and for the control group it was 0.047 +/- 0.019 mu g/100ml. This leads to the result that due to industrial plants and technological contamination people get easy sick at an early age. As a result the risk of cancer increases. We are sure that this study will contribute the future studies. Therefore it is very important that persons working in industrial zones should be more careful, and have to take relevant precautions when working.