Purpose: To compare the Schlemm's canal area (SCA) and to define iris features in patients with unilateral herpetic anterior uveitis (HAU) by using anterior segment spectral-domain optical coherence tomography (AS SD-OCT). Methods: Unilateral HAU cases that had been in complete remission for >= 3 months were included. Two investigators analyzed the iris features of HAU. SCA in both healthy (N), and affected eyes (HAU) were compared. Results: The mean age of the participants (n = 22) was 36.3 +/- 15 (17-70) years. The mean nasal and temporal (n-t) SCA was measured as 10,844 +/- 4806 mu m(2)and 8,772 +/- 3138 mu m(2)in HAU in comparison with 10,200 +/- 4,824 mu m(2)and 10,045 +/- 3,889 mu m(2)in N, respectively (p= .47 andp= .12, respectively). The most common iris features were the sectoral iridoplegia (100%) on biomicroscopy and the disorganization of the iris layers (DIL) (77%) on AS SD-OCT images. Conclusion: SCA found similar on both sides. DIL is the most common iris feature of affected eyes.