Electroanalytical determination of enrofloxacin based on the enhancement effect of the anionic surfactant at anodically pretreated boron-doped diamond electrode


Dönmez F., Yardım Y., Şentürk Z.

DIAMOND AND RELATED MATERIALS, vol.84, pp.95-102, 2018 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 84
  • Publication Date: 2018
  • Doi Number: 10.1016/j.diamond.2018.03.013
  • Journal Name: DIAMOND AND RELATED MATERIALS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.95-102
  • Keywords: Enrofloxacin, Anodically pretreated boron-doped diamond, Square-wave adsorptive stripping voltammetry, Sodium dodecyl sulfate, Pharmaceutical formulation, urine samples, ADSORPTIVE STRIPPING VOLTAMMETRY, PERFORMANCE LIQUID-CHROMATOGRAPHY, MOLECULARLY IMPRINTED POLYMER, SODIUM DODECYL-SULFATE, ELECTROCHEMICAL DETERMINATION, BIOLOGICAL-FLUIDS, BOVINE-MILK, PHARMACEUTICALS, OXIDATION, FLUOROQUINOLONES
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

In this paper, a mercury-free and modification-free electroanalytical methodology based on anodically pretreated boron-doped diamond electrode is described for the quantification of enrofloxacin. The oxidation of compound was irreversible and presented an adsorption controlled process. The sensitivity of the stripping voltammetric measurements was significantly improved when the anionic surfactant, sodium dodecylsulfate (SDS) was present in the electrolyte solution. Using square-wave stripping mode, a linear response was obtained for enrofloxacin determination in 0.1 mol L-1 HNO3 solution containing 9 x 10(-4) mol L-1 SDS at +1.27 V (vs. Ag/AgCl) (after 60 s accumulation at open-circuit condition). Linearity was found within 0.025 to 1.0 mu g mL(-1) (6.96 x 10(-8)-2.78 x 10(-6) mol L-1) with a detection limit 0.0057 mu g mL(-1) (1.59 x 10(-8) mol L-1). The proposed method could be used for the determination of enrofloxacin in pharmaceutical formulations and the spiked human urine samples with acceptable recoveries.