The effect of high dose digoxin on cytokines in healthy dogs

DULGER H., Sekeroglu M. R., ERYONUCU B., NOYAN T., ALICI U.

MEDIATORS OF INFLAMMATION, cilt.11, sa.4, ss.261-263, 2002 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11 Sayı: 4
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1080/096293502900000122
  • Dergi Adı: MEDIATORS OF INFLAMMATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.261-263
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Background: Tumor necrosis factor (TNF)-alpha and interleukin (IL)-1beta are pro-inflammatory cytokines, causing myocardial dysfunction and a negative inotropic effect. The drugs used to treat heart failure affect the production of cytokines. Digoxin, on which this study was focused, is one of the drugs for the treatment of heart failure.