The effect of high dose digoxin on cytokines in healthy dogs

DULGER, H; Sekeroglu, Mehmet; ERYONUCU, B; NOYAN, T; ALICI, U

doi:10.1080/096293502900000122

The effect of high dose digoxin on cytokines in healthy dogs

DULGER H., Sekeroglu M. R., ERYONUCU B., NOYAN T., ALICI U.

MEDIATORS OF INFLAMMATION, cilt.11, sa.4, ss.261-263, 2002 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 11 Sayı: 4
Basım Tarihi: 2002
Doi Numarası: 10.1080/096293502900000122
Dergi Adı: MEDIATORS OF INFLAMMATION
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.261-263
Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Background: Tumor necrosis factor (TNF)-alpha and interleukin (IL)-1beta are pro-inflammatory cytokines, causing myocardial dysfunction and a negative inotropic effect. The drugs used to treat heart failure affect the production of cytokines. Digoxin, on which this study was focused, is one of the drugs for the treatment of heart failure.