This study investigates the effects of multi-enzyme (xylanase, beta-glucanase, cellulase, pectinase, and protease) supplementation of wheat based quail rations on body weight, feed consumption, egg production, egg quality, feed conversion ratio and some blood parameters. A total of 210 eight-week old quails were distributed into five groups and fed diet supplemented with the multi-enzyme Rovabio Excel at 0 (Control), 0.5 (E-0.5), 1.0 (E-1.0), 1.5 (E-1.5) and 2.0 (B-2.0) kg/ton for a period of 12 weeks. Egg production and egg number increased (P < 0.01) in E-1.0 and E-1.5 groups but decreased (P < 0.01) in E-2.0. The highest (P < 0.05) average egg weight was obtained in the E-1.5 group, fed with 1.5 kg enzyme/ton. Albumen index significantly increased (P < 0.05) in all treatment groups compared to control group. The highest (P < 0.05) yolk index was recorded in the E-0.5 group fed with 0.5 kg enzyme/ton. Egg shape index increased (P < 0.05) in the E-1.0 and E-2.0 groups while the Haugh unit increased significantly (P < 0.05) in the E-1.0 and E-1.5 groups. However, egg size decreased (P < 0.05) with E-1.0. As a result, 1 and 1.5 kg enzyme/ton amounts of Rovabio Excel enzyme supplementation in wheat based quail rations increased egg production, egg number, average egg weight, albumen index, yolk index, egg shape index and Haugh unit, Minolta a* value. This results of this study suggest that multi-enzyme additives can be used to improve the performance quail fed on wheat based rations.