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Luleyap U., Aksoy G., Evyapan G., PAZARCI P., ALPTEKİN D., PAZARBAŞI A., ...More
CUKUROVA MEDICAL JOURNAL, vol.46, no.2, pp.764-771, 2021 (ESCI)
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Publication Type:
Article / Article
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Volume:
46
Issue:
2
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Publication Date:
2021
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Doi Number:
10.17826/cumj.870361
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Journal Name:
CUKUROVA MEDICAL JOURNAL
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Journal Indexes:
Emerging Sources Citation Index (ESCI), Academic Search Premier, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
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Page Numbers:
pp.764-771
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Keywords:
Alzheimer's disease, alternative splicing, sodium butyrate, HISTONE DEACETYLASES, ALZHEIMERS-DISEASE, CANCER-THERAPY, INHIBITION, APOPTOSIS, IDENTIFICATION, QUADRUPLEX
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Van Yüzüncü Yıl University Affiliated:
No
Abstract
Purpose: The aim of this study is to investigate effect of sodium butyrate (NaB), which is a Histon Deacetylase (HDAC) inhibitor, on BACE1 isoforms BACE1/501, BACE1/457 and BACE1/432 and alternative splicing factors including hnRNP H, U2AF35, U2AF65, SRSF1, SRSF2, SRSF5 and SRSF6.