JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-ENVIRONMENTAL SCIENCE AND ENGINEERING & TOXIC AND HAZARDOUS SUBSTANCE CONTROL, vol.31, no.8, pp.2017-2022, 1996 (Peer-Reviewed Journal)
Article / Article
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-ENVIRONMENTAL SCIENCE AND ENGINEERING & TOXIC AND HAZARDOUS SUBSTANCE CONTROL
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The carbonic anhydrase Isoenzymes employed here have been purifield in high yields by affinity chromatograpy using different affinity gels(Sepharose4B-L-tyrosine-Benzensulfonamide). Inhibition effect of 2-Substituted-1,3,4-Thiadiazole-5-Sulfonamides on human carbonic anhydrase-I (HCA-I) and bovine carbonic anhydrase (BCA) have been determined. It was found that inhibition effects of these compounds on BCA and CA-I were very great.