JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-ENVIRONMENTAL SCIENCE AND ENGINEERING & TOXIC AND HAZARDOUS SUBSTANCE CONTROL, cilt.31, ss.2017-2022, 1996 (SCI İndekslerine Giren Dergi)
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-ENVIRONMENTAL SCIENCE AND ENGINEERING & TOXIC AND HAZARDOUS SUBSTANCE CONTROL
The carbonic anhydrase Isoenzymes employed here have been purifield in high yields by affinity chromatograpy using different affinity gels(Sepharose4B-L-tyrosine-Benzensulfonamide). Inhibition effect of 2-Substituted-1,3,4-Thiadiazole-5-Sulfonamides on human carbonic anhydrase-I (HCA-I) and bovine carbonic anhydrase (BCA) have been determined. It was found that inhibition effects of these compounds on BCA and CA-I were very great.