International Congress (Webinar) on Life Sciences Life Sciences Virtual 2021, Pennsylvania, United States Of America, 27 - 28 January 2021, pp.35
Many Some 5,000 species of nematodes are estimated to be parasites of vertebrate animals and
humans. These species are often characterized in a larger group of worm parasites as helminths.
Nematode parasites of domestic vertebrate animals are managed by strategies that include control of
secondary hosts or vectors and the use of chemical anthelminthics. Gastrointestinal parasitic infections
in sheep cause economic losses by causing weight loss, growth retardation and anemia. It also occurs
in drug related losses. Resistance to anthelmintic drugs is an important problem all over the world.
Unconsciously used excessive medication increases the formation of resistance. Species in Haemonchus
sp., Ostertagia sp and Trichostrongylus lineages are more pathogenic and higher in mortality compared
to species in other Trichostrongylus strains. Haemonchus contortus is the most important species
known to be resistant species in small ruminants breeding worldwide. Because Haemonchus contortus
absorbs 0.05 ml of blood daily from the host, so it causes deaths especially in young people with intense
parasitemia. Therefore, the use of effective drugs against these parasites is the most effective factor in
the fight against these parasites. Studies on the subject are being conducted all over the world and the
subject is highly regarded, The Consortium for Anthelmintic Resistance and Susceptibility (CARS) meets
every two years to discuss the latest research to evaluate the anthelmintic drug resistance mechanism.
The CARS group supports anthelmintic resistance research to aid in the development of molecular
markers and new drugs for the diagnosis of anthelmintic resistance. There are a limited number of
studies on the subject in our country. The method recommended by the World Veterinary Parasitology
Development Association for the determination and monitoring of drug resistance in livestock is the
stool egg count reduction test (FECRT). Detection of resistant species can be made by molecular methods
from third stage larvae obtained by larvae culture from feces.