Studies on reactions of cyclic oxalyl compounds with hydrazines or hydrazones - 2. Synthesis and reactions of 4-benzoyl-1-(4-nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid


Sener A., Kasimogullari R., Sener M., Genc H.

KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, ss.1201-1208, 2004 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: Konu: 8
  • Basım Tarihi: 2004
  • Dergi Adı: KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII
  • Sayfa Sayıları: ss.1201-1208

Özet

4-Benzoyl-1-(4-nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid, obtained from corresponding furan-2,3-dione and N-benzylidene-N'-(4-nitrophenyl)hydrazine, was converted via reactions of its acid chloride with various alcohols or N-nucleophiles into the corresponding ester or amide derivatives. Nitrile of the starting acid 1-(4-aminophenyl)-4-benzoyl-5-phenyl-1H-pyrazole-3-carboxylic acid was also obtained. While cyclocondensation reactions of two acids and nitrile mentioned hydrazines lead to pyrazolo[3,4-d]pyridazine derivatives, the reaction of starting acid with 2-hydrazino-pyridine provided hydrazono-pyrazole acid derivative.