Studies on reactions of cyclic oxalyl compounds with hydrazines or hydrazones - 2. Synthesis and reactions of 4-benzoyl-1-(4-nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid

Sener A., Kasimogullari R., Sener M., Genc H.

KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, no.8, pp.1201-1208, 2004 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: Issue: 8
  • Publication Date: 2004
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.1201-1208
  • Van Yüzüncü Yıl University Affiliated: No


4-Benzoyl-1-(4-nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid, obtained from corresponding furan-2,3-dione and N-benzylidene-N'-(4-nitrophenyl)hydrazine, was converted via reactions of its acid chloride with various alcohols or N-nucleophiles into the corresponding ester or amide derivatives. Nitrile of the starting acid 1-(4-aminophenyl)-4-benzoyl-5-phenyl-1H-pyrazole-3-carboxylic acid was also obtained. While cyclocondensation reactions of two acids and nitrile mentioned hydrazines lead to pyrazolo[3,4-d]pyridazine derivatives, the reaction of starting acid with 2-hydrazino-pyridine provided hydrazono-pyrazole acid derivative.