Research Information System
Journal of ata-chem, vol.3, no.2, pp.32-38, 2023 (Peer-Reviewed Journal)
Nanomaterials have been widely used in many fields such as electronics, biomedicine, cosmetics and food
processing in recent years. These materials have an important place in the development of diagnosis, treatment and
prevention techniques in the field of medicine. Graphene oxide (GO), an oxidized derivative of graphene, has recently
been used in biotechnology and medicine for cancer therapy, drug delivery, and cellular imaging. GO, which is widely
used in many fields, can be characterized by various physicochemical properties, including its nanoscale size, surface
area and electric charge. In addition, the toxic effect of GO on living cells emerges as a factor limiting its use in the
medical field. In general, it has been observed that the severity of the toxic effect of this nanomaterial varies depending
on the route of administration and the dose applied. In recent years, intensive studies have been initiated on the use of
graphene-based materials, especially in smart medicine and gene technology. In this study, the electronic properties
of commercially available pyrimidine derivative compounds and their adsorption in the graphene oxide nanocage were
calculated using density functional theory (DFT).