JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, vol.138, no.5, pp.739-743, 2012 (SCI-Expanded)
Article / Article
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Bladder cancer, Nitric oxide, Total antioxidant status, Malondialdehyde, Prolidase activity, LIPID-PEROXIDATION, EXTRACELLULAR-MATRIX, COLLAGEN-METABOLISM, ANTIOXIDANT STATUS, CELL CARCINOMA, STOMACH-CANCER, BREAST-CANCER, VITAMIN-C, IMINODIPEPTIDURIA, INHIBITORS
Van Yüzüncü Yıl University Affiliated:
Prolidase is a member of the matrix metalloproteinase family. It plays a major role in collagen turnover, matrix remodeling and cell growth. Nitric oxide (NO) regulates many processes such as collagen synthesis and matrix remodeling. Thus, NO may augment angiogenesis, tumor invasion, and metastasis. The aim of this study was to investigate total antioxidant status (TAS), malondialdehyde (MDA) and NO levels in patients with bladder cancer and to determine their relationship with prolidase activity.