Serum paraoxonase-1 enzyme activities and oxidative stress levels in patients with esophageal squamous cell carcinoma

SEHITOGULLARI A., Aslan M., Sayır F., KAHRAMAN A., Demir H.

REDOX REPORT, vol.19, no.5, pp.199-205, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 5
  • Publication Date: 2014
  • Doi Number: 10.1179/1351000214y.0000000091
  • Journal Name: REDOX REPORT
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.199-205
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

Objectives: Oxidative stress is well recognized to play a role in the pathogenesis of many diseases, including cancers. Paraoxonase-1 (PON1) is implicated in the elimination of carcinogenic lipid-soluble radicals produced by lipid peroxidation. Reports on PON1 activities in patients with cancer are conflicting. The aim of this study was to investigate serum antioxidant enzyme activities and oxidative stress levels in patients with esophageal squamous cell carcinoma (ESCC).