Serum paraoxonase-1 enzyme activities and oxidative stress levels in patients with esophageal squamous cell carcinoma

SEHITOGULLARI A., Aslan M., Sayır F., KAHRAMAN A., Demir H.

REDOX REPORT, cilt.19, sa.5, ss.199-205, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 5
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1179/1351000214y.0000000091
  • Dergi Adı: REDOX REPORT
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.199-205
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Objectives: Oxidative stress is well recognized to play a role in the pathogenesis of many diseases, including cancers. Paraoxonase-1 (PON1) is implicated in the elimination of carcinogenic lipid-soluble radicals produced by lipid peroxidation. Reports on PON1 activities in patients with cancer are conflicting. The aim of this study was to investigate serum antioxidant enzyme activities and oxidative stress levels in patients with esophageal squamous cell carcinoma (ESCC).