The Effect of Tarantula cubensis (Theranekron) on Some Reproductive Parameters in Male Rats


Creative Commons License

Koşal V., Keleş Ö. F.

Iranian Journal of Veterinary Medicine, cilt.17, sa.2, ss.107-112, 2023 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 2
  • Basım Tarihi: 2023
  • Doi Numarası: 10.32598/ijvm.17.2.1005343
  • Dergi Adı: Iranian Journal of Veterinary Medicine
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.107-112
  • Anahtar Kelimeler: Rat, Sperm, Tarantula cubensis, Testis, Theranekron
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Background: Tarantula cubensis (theranekron), obtained from the poison of Cuban Tarantula, is a homeopathic drug frequently used in animal health. Objectives: The effect of theranekron on reproductive parameters in male animals is unknown. In this study, the effect of theranekron on male reproductive parameters was investigated. Methods: Three different groups of rats were created: control (n=8) (no application), theranekron I (n=8) (subcuteneous injection of 0.3 mg/kg on days 0, 5, and 10), and theranekron II (n=8) (subcuteneous injection of 0.3 mg/kg on days 0, 5, and 10). Control and theranekron I groups were sacrificed at the end of the 4 weeks, and the theranekron II group was sacrificed at the end of the 6 weeks. Sperm motility, density, abnormal rate, DNA damage, and testicular histopathology were examined. Results: No statistical difference was observed in the parameters examined between the study groups (P>0.05). It was determined that the theranekron did not change sperm motility, density and spermatozoa ratio, also no histopathological changes, and sperm DNA damage. Conclusion: There is no harm in using theranekron in male animals during the breeding and nonbreeding seasons.