Poly(3-(acrylamidopropyl)trimethyl ammonium chloride) Hydrogels Incorporated with Gold Nanoparticles via Verbascum Longipedicellatum Extract for Antibacterial Applications

9th International Mardin Artuklu Scientific Researches Conference, Mardin, Türkiye, 20 - 22 Ocak 2023, ss.1-360, (Özet Bildiri)

Recently, green nanotechnology for the synthesis of environmentally-friendly nanoparticles has gaining

more attention in biomedical applications due to its non-toxicity and low-cost synthesis approach. Here, the

in-situ synthesis of poly(3-(acrylamidopropyl)trimethyl ammonium chloride) nanocomposite hydrogel,

p(APTMAC) containing gold nanoparticles in aqueous medium using ecofriendly, non-toxic, cost effective

and easily available Verbascum Longipedicellatum plant extract as reducing and stabilizing agent was

reported. The structure and morphology of the p(APTMAC)hydrogel were confirmed by Fourier transform

infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). The crystallinity and morphology of

the p(APTMAC)-Au nanocomposite hydrogel were confirmed by X-ray diffraction analysis (XRD) and

transmission electron microscopy-energydispersive X-ray spectroscopy (TEM-EDX), X-ray diffraction

analysis (XRD). The p(APTMAC)hydrogel and p(APTMAC)-Au nanocomposite hydrogel were tested

against Gram-negative bacteria Escherichia coli and Gram-positive bacteria Staphylococcus aureus for their

antibacterial properties. The results indicate that p(APTMAC)-Au nanocomposite hydrogel exhibited higher

antimicrobial activity than the p(APTMAC)-hydrogel. Therefore, novel gold nanoparticle embedded

hydrogels can be used as potential candidates for antibacterial applications. Besides, it has a number of

applications such as catalysis, biosensors and biomedical devices.