The role of pentraxin 3 in pemphigus vulgaris


Yavuz İ. H. , Özaydın Yavuz G.

POSTEPY DERMATOLOGII I ALERGOLOGII, cilt.37, ss.503-507, 2020 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 37 Konu: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5114/ada.2019.81234
  • Dergi Adı: POSTEPY DERMATOLOGII I ALERGOLOGII
  • Sayfa Sayıları: ss.503-507

Özet

Introduction: Pemphigus is a group of autoimmune bullous diseases caused by antibodies directed against the desmosomal adhesion molecules desmoglein land 3, which are required for intercellular adhesion of keratinocytes. Pentraxins are a group of proteins that function as pattern recognition molecules and also play a role in humoral innate immunity. Pentraxin 3 (PTX3) is the prototype of the long pentraxins and has been shown to be increased in numerous autoimmune diseases.