The role of pentraxin 3 in pemphigus vulgaris


Yavuz İ. H. , Özaydın Yavuz G.

POSTEPY DERMATOLOGII I ALERGOLOGII, vol.37, no.4, pp.503-507, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 4
  • Publication Date: 2020
  • Doi Number: 10.5114/ada.2019.81234
  • Journal Name: POSTEPY DERMATOLOGII I ALERGOLOGII
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, Directory of Open Access Journals
  • Page Numbers: pp.503-507
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

Introduction: Pemphigus is a group of autoimmune bullous diseases caused by antibodies directed against the desmosomal adhesion molecules desmoglein land 3, which are required for intercellular adhesion of keratinocytes. Pentraxins are a group of proteins that function as pattern recognition molecules and also play a role in humoral innate immunity. Pentraxin 3 (PTX3) is the prototype of the long pentraxins and has been shown to be increased in numerous autoimmune diseases.