Investigation of the protective effect of thymoquinone of U87 cells induced by beta-amyloid

Ozbolat G., Alizade A.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.122, sa.10, ss.748-752, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 122 Sayı: 10
  • Basım Tarihi: 2021
  • Doi Numarası: 10.4149/bll_2021_120
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.748-752
  • Anahtar Kelimeler: thymoquinone, amyloid-beta, U87, SOD, CAT, caspase-3, ALZHEIMERS-DISEASE, ACTIVATION, CASPASE-3, ANTIOXIDANT, DEMENTIA, BRAIN
  • Van Yüzüncü Yıl Üniversitesi Adresli: Hayır

Özet

BACKGROUND: Thymoquinone (TQ) is the active compound extracted from Nigella sativa which has been reported to possess various pharmacological attributes. This study shows that Thymoquinone (TQ) is an Alzheimer's disease (AD) model cell line on amyloid-beta (A beta)-induced U87 (human astrocytoma cell line) in beta-amyloid (A beta)-induced in vitro Alzheimer's Disease (AD) model.