IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, vol.43, no.3, pp.353-369, 2021 (SCI-Expanded)
Article / Article
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
Cyclophosphamide, immunomodulatory effect, myricetin, apigenin, hesperidin, OXIDATIVE STRESS, ANTIINFLAMMATORY ACTIVITY, INTERFERON-GAMMA, ETHANOL EXTRACT, IN-VITRO, POLYSACCHARIDE, PROLIFERATION, MECHANISMS, TOXICITY, DAMAGE
Van Yüzüncü Yıl University Affiliated:
Aim: Major side effects of cyclophosphamide administration are immunosuppression and myelosuppression. The immunomodulatory effects of plant bioactive compounds on chemotherapy drug-induced immunosuppression may have significant effects in cancer treatment. For this reason, we investigated the immunomodulatory effect of myricetin, apigenin, and hesperidin in cyclophosphamide-induced immunosuppression in rats.