Comparison of monocyte with high density lipoprotein cholesterol ratio in dipper and nondipper hypertensive patients


Selcuk M., Yildirim E., Saylik F.

BIOMARKERS IN MEDICINE, cilt.13, ss.1289-1296, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 13 Konu: 15
  • Basım Tarihi: 2019
  • Doi Numarası: 10.2217/bmm-2019-0062
  • Dergi Adı: BIOMARKERS IN MEDICINE
  • Sayfa Sayıları: ss.1289-1296

Özet

Aim: We aimed to compare the monocyte to HDL-cholesterol ratio (MHR) of nondipper hypertension (NDHT) and dipper hypertension patients. Patients & methods: A total of 162 patients were included in the study. Patients were grouped as dipper and nondipper according to 24-h ambulatory blood pressure recordings. Results: The MHR was significantly higher in nondipper hypertension group compared with control (p < 0.001) and dipper hypertension groups (p = 0.03). MHR, hs-CRP and red-cell distribution width (RDW) were independent predictors of nondipper hypertension. Area under the curve was 0.62 (p = 0.034) for MHR and 0.61 (p = 0.012) for hs-CRP in the ROC analysis. Conclusion: MHR has elevated levels in NDHT patients. Increased levels of MHR may evaluate as increased risk of cardiovascular events in NDHT patients.