Follow-up of Patients Who Received Palliative Lung Radiotherapy: A Single Center Experience

Çukurova Anestezi ve Cerrahi Bilimler Dergisi, cilt.8, sa.3, ss.251-256, 2025 (TRDizin)

Aim: This study conducted retrospectively aims to examine the relationship between survival time and some

biochemical features in stage-4 patients who received palliative RT to their lungs.

Methods: Fifty-one patients who received palliative lung radiotherapy between July 2016 and May 2022 were

included in the study. All patients; age, survival rate, gender and type of carcinoma [non-small cell lung cancer

(NSCLC) and small cell lung cancer (SCLC)]; some biochemical features were measured. For comparing groups,

independent groups t-test and Mann–Whitney U test was used for normally and non-normally distributed features,

respectively. Pearson correlation analysis was performed to determine the linear relationships between variables.

Kaplan-Meier method was used to determine overall and groups’ survival time.

Results: All patients had stage 4 LC, 41 (80.39%) of these were in the NSCLC group and 10 (19.61%) in the SCLC

group. The overall median survival time was 16 weeks, while the survival time in the NSCLC and SCLC groups was

18 and 4 weeks, respectively. For the considered features, except for the ALT, no difference between the groups

was found statistically significant. ALT values were approximately two times higher in the SCLC group.

Conclusions: The results of this study indicated that no significant relationship was found between survival time

and considered biochemical features. However, it was observed that survival time of carcinoma groups was

considerably different. Further research needs to examine more closely the relationships between survival time

and some biochemical features in stage-4 patients who received palliative RT.