FRESENIUS ENVIRONMENTAL BULLETIN, cilt.21, sa.6, ss.1417-1421, 2012 (SCI-Expanded)
The micronucleus assay (MNT) is a mutagenicity test system for determining pollution and chemicals causing changes in DNA fragments, such as micronuclei (MN) in the cytoplasm of interphase cells. Damage caused in the DNA by genotoxic pollutants is the first consequence occurring in the aquatic organisms. The MNT in fish erythrocytes has increasingly been used to detect the genotoxic effects of environmental mutagens, and its frequency is considered to reflect the genotoxic damage to cells, mainly the chromosomes.