First Electroanalytical Methodology for the Determination of Hordenine in Dietary Supplements using a Boron-doped Diamond Electrode

ALLAHVERDIYEVA S., Keskin E., PıNAR P., Yardım Y., Şentürk Z.

ELECTROANALYSIS, vol.31, no.11, pp.2283-2289, 2019 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 11
  • Publication Date: 2019
  • Doi Number: 10.1002/elan.201900365
  • Journal Name: ELECTROANALYSIS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2283-2289
  • Keywords: Boron-doped diamond electrode, Dietary supplement, Hordenine, Square-wave voltammetry, LIQUID-CHROMATOGRAPHY, UPLC-MS/MS, ALKALOIDS, PHENETHYLAMINES, PLASMA, RAT
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

The present work describes the first electrochemical investigation and a simple, rapid and modification-free electroanalytical methodology for quantification of hordenine (a potent phenylethylamine alkaloid) using a boron-doped diamond electrode. At optimized square-wave voltammetric parameters, the observed oxidation peak current in 0.1 M HClO4 at +1.33 V (vs. Ag/AgCl) increased linearly from 5.0 to 100 mu g mL(-1) (3.0x10(-5)-6.1x10(-4) M), with detection limit of 1.3 mu g mL(-1) (7.8x10(-6) M). The applicability of the developed method was tested with the determination of hordenine in the commercial dietary supplement formulations.