Dialysis therapy for lactic acidosis caused by metformin intoxication: presentation of two cases

Soyoral Y. U. , Begenik H. , Emre H. , Aytemiz E., Ozturk M., Erkoc R.

HUMAN & EXPERIMENTAL TOXICOLOGY, cilt.30, sa.12, ss.1995-1997, 2011 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Konu: 12
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1177/0960327111403177
  • Sayfa Sayıları: ss.1995-1997


Metformin is an oral antidiabetic, which is frequently used in the treatment of type II diabetes mellitus. Serious side effects may be seen during the administration of high doses of metformin. Two cases of lactic acidosis due to ingestion of high dose metformin for suicidal purposes have been presented here; in both cases, clinical improvement was seen with bicarbonate hemodialysis.