Electrochemical Dopamine Sensor Based on Gold Nanoparticles Electrodeposited on a Polymer/Reduced Graphene Oxide-Modified Glassy Carbon Electrode

Güler M., Kavak E., KIVRAK A.

ANALYTICAL LETTERS, cilt.55, sa.7, ss.1131-1148, 2022 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 55 Sayı: 7
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1080/00032719.2021.1990310
  • Dergi Adı: ANALYTICAL LETTERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, Communication Abstracts, Food Science & Technology Abstracts, Metadex, Veterinary Science Database, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.1131-1148
  • Anahtar Kelimeler: Amperometry, cyclic voltammetry (CV), differential pulse voltammetry (DPV), dopamine sensor, gold nanoparticles, poly([2, 2 ',5 ', 2 '']-terthiophene-3 '-carbaldehyde) [poly(TTP)], reduced graphene oxide, VOLTAMMETRIC DETERMINATION, COMPOSITE, PERFORMANCE, MODULATION, SEPARATION, RECEPTORS, COMPLEXES, SEROTONIN, BIOSENSOR, DISEASE
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

A novel electrochemical dopamine (DA) sensor based on Au nanoparticles (AuNPs) electrochemically loaded on poly([2,2 ';5 ',2 '']-terthiophene-3 '-carbaldehyde)/reduced graphene oxide (poly(TTP)/rGO) improved glassy carbon electrode (GCE) was fabricated. The Au@poly(TTP)/rGO/GCE was evaluated using cyclic voltammetry (CV), differential pulse voltammetry (DPV), amperometry, and electrochemical impedance spectroscopy (EIS). The optimized Au@poly(TTP)/rGO/GCE sensor had a wide electroactive surface area and exhibited good selectivity. The linear determination range of the sensor was from 0.02 to 232 mu M with a sensitivity of 315 mu A/mM/cm(2). The limit of detection (LOD) was estimated to be 11.5 nM using signal-to-noise (S/N) ratio of 3. Additionally, the sensor displayed excellent selectivity, satisfactory response time from 4.5 to 6 s, replicability with a relative standard deviation (RSD) of 2.31%, reproducibility with a RSD of 3.67%, and storage stability with 92.57% of its initial current response for 37 days. The Au@poly(TTP)/rGO/GCE was employed to estimate DA in injection samples.