Effects of Sentinel Lymph Node Dissection on Sexual Function After Endometrial Cancer Surgery


Simsek E., Yildiz S., Karakas S., Karaaslan O., Gunduz S., Yildiz O. A., ...Daha Fazla

Haseki Tip Bulteni, cilt.63, sa.4, ss.218-223, 2025 (ESCI, Scopus, TRDizin) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 63 Sayı: 4
  • Basım Tarihi: 2025
  • Doi Numarası: 10.4274/haseki.galenos.2025.69775
  • Dergi Adı: Haseki Tip Bulteni
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, EMBASE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.218-223
  • Anahtar Kelimeler: endometrial neoplasms, quality of life, Sentinel lymph node, sexual dysfunction
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Aim: The purpose of this research was to determine whether endometrial cancer (EC) patients’ sexual function (SF) and quality of life (QoL) were affected by sentinel lymph node dissection (SLND). The effects on SF of SLND and pelvic and paraaortic lymph node dissection (LND) in the surgical treatment of EC were compared. Methods: This prospective, single-center research comprised 82 individuals who had LND for endometrial cancer. Patients were categorized into two groups based on the extent of LND: Group A SLND and Group B (pelvic and/or para-aortic lymphadenectomy). The Female Sexual Function Index (FSFI) and the Functional Assessment of Cancer Therapy (FACT-G) were used to measure SF and QoL, respectively, six months after surgery. Results: Among the 82 patients, 14 (17%) retained normal SF (FSFI ≥26.55), while 68 (83%) experienced sexual dysfunction. While no substantial difference was seen in overall FSFI scores among the groups, patients in the SLN group had significantly higher ratings in the desire (p=0.036) and orgasm (p=0.042) subdomains compared to the other groups. Quality of life, as assessed by the FACT-G, was negatively impacted by lower SF scores, particularly among highly educated patients (p=0.013). Conclusion: Sentinel lymph node dissection may preserve aspects of female SF in patients undergoing surgery for endometrial carcinoma, especially in younger and more educated patients.