PARASITOLOGISTS UNITED JOURNAL, cilt.0, sa.0, ss.299-303, 2026 (ESCI)
Background: Species of microsporidia can cause pulmonary microsporidiosis by colonizing the lower respiratory tract of the host.
Objective: To investigate the frequency of microsporidial spores in immunocompetent patients with lung disease.
Subjects and Methods: This cross-sectional study included 65 patients admitted to Dursun Odabaş Medical Center, Van Yüzünücü Yıl University, who had undergone bronchial lavage (BAL), and were confirmed HIV-negative. Patients with conditions that weaken the immune system, such as cancer, chronic obstructive pulmonary disease (COPD), or chronic kidney failure, or those who were taking immunosuppressive medications were excluded from the study. To investigate the presence of microsporidia, BAL samples obtained from patients were examined using modified trichrome staining and conventional PCR.
Results: Examinations identified pulmonary microsporidiosis in three patients (4.62%) by molecular analysis, whereas only one of these cases (1.54%) was confirmed by the modified trichrome staining method.
Conclusion: As a result, we believe that microsporidiosis should be considered in patients with lung disease, regardless of the immune status.