Serum Total Sialic Acid and Lipid-linked Sialic Acid May Be the New Potential Biomarkers in Paracetamol Nephrotoxicity

Öksüz E., Bugday M. S., Demir F., Ekin S., Arıhan O., Oto G.

TURKISH JOURNAL OF NEPHROLOGY, cilt.29, sa.4, ss.273-278, 2020 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5152/turkjnephrol.2020.4310
  • Dergi Adı: TURKISH JOURNAL OF NEPHROLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.273-278
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Objective: In recent years, paracetamol has been shown to have toxic effects on the kidneys. Sialic acid (SA), an important component of the cell membranes, increases in many pathological conditions. This study aimed to investigate the effects of different doses of paracetamol on the kidney tissue and serum total SA (TSA) and lipid-bound SA (LSA) levels.