Serum Total Sialic Acid and Lipid-linked Sialic Acid May Be the New Potential Biomarkers in Paracetamol Nephrotoxicity


Öksüz E. , Bugday M. S. , Demir F. , Ekin S. , Arıhan O. , Oto G.

TURKISH JOURNAL OF NEPHROLOGY, vol.29, no.4, pp.273-278, 2020 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 4
  • Publication Date: 2020
  • Doi Number: 10.5152/turkjnephrol.2020.4310
  • Title of Journal : TURKISH JOURNAL OF NEPHROLOGY
  • Page Numbers: pp.273-278

Abstract

Objective: In recent years, paracetamol has been shown to have toxic effects on the kidneys. Sialic acid (SA), an important component of the cell membranes, increases in many pathological conditions. This study aimed to investigate the effects of different doses of paracetamol on the kidney tissue and serum total SA (TSA) and lipid-bound SA (LSA) levels.