Effect of Urtica dioica L. on selected trace elements levels and serum protein patterns in the rabbits treated with 7,12-Dimethylbenz(a)anthracene


Ekin S. , Oto G. , Berber I., Türel I., KUSMAN T.

ASIAN JOURNAL OF CHEMISTRY, cilt.20, ss.5704-5710, 2008 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 20 Konu: 7
  • Basım Tarihi: 2008
  • Dergi Adı: ASIAN JOURNAL OF CHEMISTRY
  • Sayfa Sayıları: ss.5704-5710

Özet

In the present study, the effect of Nettle (Urtica dioca L.) on trace elements and serum protein patterns in female rabbits administrated to 7,12-Dimethylbenz(a)anthracene (DMBA) was investigated. Rabbits were divided into equal four groups. Group I was control group (n = 8), group 11 (n = 8), treated with DMBA (1 mg/kg.d), group III treated with DMBA (I mg/kg.d) and methanol extract of U. dioica 35 mg/kg/d and group IV (n = 8) treated with DMBA (1 mg/kg.d) and aqueous extract of U. dioica 35 mg/kg/d. The results show that on 60th day DMBA-treated group were compared with the control group levels, a significant decrease (p < 0.05) was observed in the Zn. DMBA and methanol extract of U. dioica treated group were compared with the control group levels, a significant increase (p < 0.05) was observed in the Cu. Serum Fe and Mn levels among groups were determined not to be statistically significant (p > 0.05). It was found that U. dioica not affected on trace elements level and serum protein patterns in rabbits subjected to DMBA.