Investigation of the relationship between hemophilia joint health score and haemophilia early arthropathy detection with ultrasound score in hemophilic arthropathy Hemofilik artropatide hemofili eklem sağlığı skoru ve hemofili erken artropati taraması ultrason skoru arasındaki ilişkinin araştırılması


Uğur M. C. , TAMSEL İ., Tat N. M. , Kavakli K.

Turkiye Klinikleri Journal of Medical Sciences, vol.41, no.1, pp.46-50, 2021 (Journal Indexed in SCI Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.5336/medsci.2020-78772
  • Title of Journal : Turkiye Klinikleri Journal of Medical Sciences
  • Page Numbers: pp.46-50
  • Keywords: Arthropathy, Hemophilia A, Hemophilia B

Abstract

© 2021 by Türkiye Klinikleri.Objective: Hemophilia is classified according to the factor VIII or IX level as severe, moderate and mild. The Hemophilia Joint Health Score (HJHS) and Haemophilia Early Arthropathy Detection with Ultrasound (HEAD-US) score used in recent years contribute significantly to the early diagnosis of arthropathy, which continues to be an important problem in severe hemophilia. It was aimed to investigate the compatibility between HJHS and HEAD-US scores. Material and Methods: The demographic and disease-related data, HJHS 2.1 and HEAD-US scores of the participants who participated in the Workshop of the Hemophilia Federation in 2020 were recorded. Results: The mean age of 32 participants was 20.6 (minimum: 15-maximum: 31). Twenty three were diagnosed as Hemophilia A, 8 were Hemophilia B, 1 was Von Willebrand disease. HJHS score of 30 patients was 6.7±6.2 (minimum: 0-maximum: 22). The mean of HEAD-US was 14.3±11.5 (minimum: 0-maximum: 34). HJHS and HEAD-US scores were compatible with each other (p=0.002). Arthropathy was present in 33 joints of 21 patients. There was a statistical significance between patients with and without arthropathy with both the HJHS and the HEAD-US scores (0.006 and 0.005 respectively). The most common arthropathy is in the right knee. HJHS and HEAD-US scores are compatible in both knee and elbow joints. Nonetheless, it is incompatible in both ankles. HJHS and HEAD-US scores were discordant in 21 joints of 7 patients. These joints were right ankle (n=7), left ankle (n=6), left elbow (n=4), right elbow (n=2) and right knee (n=2). Conclusion: A correlation was found between the HJHS and HEAD-US scores. HEAD-US is more sensitive than HJHS in detecting the early stage of arthropathy in the ankle joint. These scores should be done routinely to all patients for manifesting treatment deficiencies and incompatibilities.