We report the concentrations of superoxide dismutase (SOD), glutathione peroxidase (GSN-Px) and malonaldialdehyde (MDA) an end product of lipoperoxidation in human whole blood. Method for measuring was the based on spectrophotometer. Blood MDA level was higher in elderly than in children, adults. Smoking, alcohol taking, acute exercise and air pollution group's MDA levels were increased than their control groups. GSH-Px activity was significantly lower in acute exercise group, and higher in trained group than those of controls. SOD was decreased in elderly, smoking and acute exercise groups and increase in trained individuals. As a result the mean values we obtained were slightly significant in age groups. The life style, environment has polluted air and habits are thought to be responsible for these significance also.