Evaluation of the Effect of Various Therapeutic Agents on Osseointegration of Dental Implants: Complications in A Rabbit Tibia Model


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Talmaç A. C., Ege B., Alpaslan N. Z., Çalışır M.

Van Health Sciences Journal, vol.16, no.2, pp.183-188, 2023 (Peer-Reviewed Journal)

Abstract

ABSTRACT Objective: The aim of our study is to evaluate the complications that occurred on rabbit tibia bones after implant placement. Material and Method: In our study, 10 adult male white healthy New Zealand rabbits (average weight: 3,000 to 3,500 g) were used. Different numbers of dental implants were placed in the experimental animals. Complications in rabbit tibias were observed and radiological results were reported. Results: Of the 10 rabbits included in the postoperative study, one (10%) died immediately after the operation, eight (80%) within the first 24 hours, and the last one (10%) died within the next 48 hours of the operation. Conclusion: Based on the complications experienced during this study and the data we obtained, we conclude that the rabbit tibia is not suitable for such studies. More comprehensive and multi-center studies are needed to draw more firm conclusions on this subject. Keywords: Dental implant, Experimental animals, Rabbit, Complications