DNA-positive, IgM-negative symptomatic congenital cytomegalovirus infection: Two case reports

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Atıf İçin Kopyala

Kirimi E., Peker E., Tuncer O., Ozkan M., Ozmen B., Ceylan A.

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, cilt.23, sa.7, ss.725-727, 2010 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 23 Sayı: 7
• Basım Tarihi: 2010
• Doi Numarası: 10.3109/14767050903222700
• Dergi Adı: JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.725-727
• Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

The characteristics of two newborns that had clinical symptoms of congenital cytomegalovirus have been presented here, whose CMV-DNA was found to be positive by the PCR method, despite serological analysis being negative for CMV IgM. In conclusion, when congenital CMV infection is suspected in newborns, it should not be forgotten that the sensitivity of serological CMV IgM assay is 70% and other methods such as CMV-DNA analysis should be performed in case of negative test results.