Aqueous TPGS-750-M-mediated synthesis of pyrano[2,3-c]-pyrazoles: a sustainable and efficient approach
Research on Chemical Intermediates, cilt.50, sa.6, ss.2827-2840, 2024 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 50 Sayı: 6
- Basım Tarihi: 2024
- Doi Numarası: 10.1007/s11164-024-05280-y
- Dergi Adı: Research on Chemical Intermediates
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Chemical Abstracts Core, Chimica, Compendex, Environment Index
- Sayfa Sayıları: ss.2827-2840
- Anahtar Kelimeler: Eco-friendly catalyst, Green chemistry, Multi-component reactions, Sustainable chemistry, Vitamin E
- Van Yüzüncü Yıl Üniversitesi Adresli: Evet
Özet
The article describes a green and efficient synthesis method for pyrano[2,3-c]-pyrazoles, employing DL-alpha-tocopherol methoxypolyethylene glycol succinate solution (TPGS-750-M) as a green and biodegradable surfactant in water. The utilization of water as a reaction medium and TPGS-750-M as a surfactant obviates the necessity for organic solvents, thereby enhancing the environmental sustainability of the synthesis. The compounds synthesized using this novel method was characterized using various spectroscopic techniques, including 1H-NMR, 13C-NMR, and mass spectrometry. Graphical abstract: (Figure presented.)