Could edaravone prevent gentamicin ototoxicity? An experimental study
HUMAN & EXPERIMENTAL TOXICOLOGY, cilt.36, sa.2, ss.123-127, 2017 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 36 Sayı: 2
- Basım Tarihi: 2017
- Doi Numarası: 10.1177/0960327116639360
- Dergi Adı: HUMAN & EXPERIMENTAL TOXICOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.123-127
- Van Yüzüncü Yıl Üniversitesi Adresli: Evet
Özet
Objectives: Clinical application of gentamicin may cause nephrotoxicity and ototoxicity. Our study is the first study to investigate the protective effects of edaravone against the gentamicin-induced ototoxicity. We investigated the protective effect of intraperitoneal (i.p.) edaravone application against gentamicin-induced ototoxicity in guinea pigs.