Could edaravone prevent gentamicin ototoxicity? An experimental study


Turan M. , CIGER E., ARSLANOGLU S., Borekci H., ONAL K.

HUMAN & EXPERIMENTAL TOXICOLOGY, vol.36, no.2, pp.123-127, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 2
  • Publication Date: 2017
  • Doi Number: 10.1177/0960327116639360
  • Title of Journal : HUMAN & EXPERIMENTAL TOXICOLOGY
  • Page Numbers: pp.123-127

Abstract

Objectives: Clinical application of gentamicin may cause nephrotoxicity and ototoxicity. Our study is the first study to investigate the protective effects of edaravone against the gentamicin-induced ototoxicity. We investigated the protective effect of intraperitoneal (i.p.) edaravone application against gentamicin-induced ototoxicity in guinea pigs.