Could edaravone prevent gentamicin ototoxicity? An experimental study


Turan M. , CIGER E., ARSLANOGLU S., Borekci H., ONAL K.

HUMAN & EXPERIMENTAL TOXICOLOGY, cilt.36, ss.123-127, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 36 Konu: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1177/0960327116639360
  • Dergi Adı: HUMAN & EXPERIMENTAL TOXICOLOGY
  • Sayfa Sayısı: ss.123-127

Özet

Objectives: Clinical application of gentamicin may cause nephrotoxicity and ototoxicity. Our study is the first study to investigate the protective effects of edaravone against the gentamicin-induced ototoxicity. We investigated the protective effect of intraperitoneal (i.p.) edaravone application against gentamicin-induced ototoxicity in guinea pigs.