Toward a Monte Carlo-driven 3D dose verification framework for IMRT: A pilot implementation for nasopharyngeal carcinoma
Radiation Physics and Engineering, cilt.7, sa.2, ss.45-55, 2026 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 7 Sayı: 2
- Basım Tarihi: 2026
- Doi Numarası: 10.22034/rpe.2026.555376.1315
- Dergi Adı: Radiation Physics and Engineering
- Derginin Tarandığı İndeksler: Scopus, Applied Science & Technology Source, Directory of Open Access Journals
- Sayfa Sayıları: ss.45-55
- Anahtar Kelimeler: Dose verification, Intensity-Modulated Radiation, Monte Carlo code, Patient-specific QA, Therapy (IMRT)
- Van Yüzüncü Yıl Üniversitesi Adresli: Evet
Özet
Monte Carlo (MC) methods are considered a complementary method for dose verification in radiation therapy. This study aims to simulate the Artiste head and the Siemens 160 Multileaf Collimator (MLC) using MCNPX 2.6.0 to enhance dose verification accuracy in Intensity-Modulated Radiation Therapy (IMRT) treatment plans. The MC-based calculations were benchmarked against commissioning-measured data and an MLC test field. A comparison between MC-based and treatment planning system (TPS)-based dose maps was made for beams of a typical complicated IMRT plan. The results demonstrated a 3D gamma passing rate (GPR) of 97.1% with 3%/3mm criteria and a 10% dose threshold, indicating the accuracy of the MC model. Based on the acceptable GPRs, the provided model has sufficient accuracy. It has been confirmed that the MC calculations can be carried out within a reasonable computation time, taking approximately 10 minutes per beam and less than 2 hours for a typical 9-beam IMRT plan. This is possible with a specific, powerful CPU configuration used for MC verification of such a complicated IMRT plan.