Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data


Muthuri S. G. , Venkatesan S., Myles P. R. , Leonardi-Bee J., Al Khuwaitir T. S. A. , Al Mamun A., ...More

LANCET RESPIRATORY MEDICINE, vol.2, no.5, pp.395-404, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 2 Issue: 5
  • Publication Date: 2014
  • Doi Number: 10.1016/s2213-2600(14)70041-4
  • Title of Journal : LANCET RESPIRATORY MEDICINE
  • Page Numbers: pp.395-404

Abstract

Background Neuraminidase inhibitors were widely used during the 2009-10 influenza A H1N1 pandemic, but evidence for their effectiveness in reducing mortality is uncertain. We did a meta-analysis of individual participant data to investigate the association between use of neuraminidase inhibitors and mortality in patients admitted to hospital with pandemic influenza A H1N1pdm09 virus infection.